Human Breast Cancer 21 Genes Expression Detection Kit
Multiplex Fluorescence PCR
Human Breast Cancer 21 Genes Expression Detection Kit
Evaluate the risk of recurrence and the benefit of chemotherapy on patients with ER+ and HER2- invasive breast cancer through 21 gene detection, which is helpful for a clinical Selectingion of appropriate treatment options.
DETECTED GENES

Breast cancer is the most common tumor in women and one of the leading causes of cancer death in women. Breast cancer 21 gene detection is a quantitative detection of the mRNA expression of 21 breast cancer-related genes. The gene expression is converted into a recurrence score ( RS ) by a specific algorithm. The results can provide information for prognosis, recurrence, and treatment guidance.


The NCCN guideline recommends 21 gene detection for adjuvant chemotherapy evaluation in patients with HR + / HER2- / N0 ~ 1 breast cancer, and ASCO and CSCO breast cancer guidelines are also strongly recommended.


DETECTED GENES
PRODUCT INFORMATION
Project Name
Core Technology
Pack Size
Instruments Validated
Sample Type
Human Breast Cancer 21 Genes Expression Detection Kit
PAP-ARMS®
6 Tests/Kit
ABI7500, ABI7300, ABI StepOne Plus, LightCycler480, Bio-Rad CFX96, etc.
Tumor Tissue
APPLICABLE POPULATION

​HR + / HER2-/ NO ~ 1 breast cancer patients

DETECTION SIGNIFICANCE


Patients with HR+ and HER2- invasive breast cancer can evaluate the risk of recurrence and the benefit of chemotherapy through 21 gene detection, which is helpful for a clinical selection of appropriate treatment options.


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FEATURES & ADVANTAGES
Preferred Recommendation

Preferred Recommendation

NCCN guidelines preferred gene expression assay, which can predict the efficacy of chemotherapy and evaluate prognosis

Rigorous Data

Rigorous Data

Through a large number of clinical studies ( retrospective, prospective ) and clinical practice, the test results are more reliable

Interpretation Science

Interpretation Science

RS values were divided into three groups of high, medium and low risk, and stratified statistics of lymph node status and menopausal status factors were included to evaluate the prognosis of patients and guide adjuvant therapy in more detail

Fast Detection

Fast Detection

The use of eight pipe pre-packing form, reduce the operation steps, improve the detection efficiency

Stable and Reliable

Stable and Reliable

The use of capping agent anti-pollution system, effectively avoid cross-contamination, improve detection specificity

DETECTION PROCESS

1.Nucleic acid extraction

2.Set up qPCR

3.Amplification

4.Data analysis

5.Report generation