ROS1 Fusion Gene Detection Kit
Mutiplex Fluorescence PCR
ROS1 Fusion Gene Detection Kit
Selecting patients for the targeted treatment of NSCLC based on the presence of ROS1 gene fusion.
BACKGROUND


Human ROS1 gene belongs to the tyrosine kinase insulin receptor gene and is involved in cell growth, proliferation, differentiation and survival. The fusion of ROS1 gene will continue to activate the ROS1 tyrosine kinase region and downstream signaling pathways such as JAK/STAT, PI3K/AKT, RAS/MAPK, etc., thus causing the occurrence and development of tumors.


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DETECTION CONTENT

PRODUCT INFORMATION
Project Name
Core Technology
Pack Size
Instruments Validated
Sample Type
ROS1 Fusion Gene Detection Kit
PAP-ARMS®
20 Tests/Kit
ABI7500, ABI7300, ABI StepOne Plus, LightCycler480, Bio-Rad CFX96, etc.
Tumor tissue,Pleural effusion &Ascites
APPLICABLE PEOPLE & DETECTION SIGNIFICATION

For patients with non-small cell lung cancer before targeted drug therapy, the appropriate targeted drug is selected through testing.

FEATURES & ADVANTAGES
Fast Detection

Fast Detection

The detection process takes only 1 working day

High Accuracy

High Accuracy

Closed tube testing is adopted to effectively avoid cross contamination

High Sensitivity

High Sensitivity

Fusion mutations containing as few as 100 copies in 40ng RNA samples can be detected

Simple Operation

Simple Operation

The process is standardized and the experimental procedure is simple

DETECTION PROCESS

1. Nucleic acid extraction

2. Set up qPCR

3. Amplification

4.Data analysis